Understanding lower limb muscle volume adaptations to amputation

Amputation of a major limb, and the subsequent return to movement with prosthesis, requires development compensatory strategies account for loss. Such strategies, over time, lead regional muscle atrophy hypertrophy through chronic under or overuse muscles compared uninjured individuals. The aim this study was quantify lower limb parameters persons transtibial transfemoral amputations using high resolution MRI ascertain volume determine regression equations predicting femur- tibia-length, pelvic-width, height, mass. Twelve loss participated in their data were six matched control subjects. Subjects unilateral amputation showed whole-limb residual-limb, whereas minor changes intact found, providing evidence compensation strategy that is dominated by intact-limb. bilateral-transfemoral significant increases short adductor an insertion not affected amputation, hip flexors, gluteus medius, decreases longer muscles, rectus femoris, hamstrings. This presents benchmark measure discrepancies limb-loss, can be used understand limb-loss impact on volume, thus enabling optimised intervention protocols, conditioning therapies, surgical techniques, prosthetic devices promote enhance functional capability within population